Action potential broadening is not a universal feature of homeostatic plasticity in response to chronic activity deprivation.
Claims
Action potential broadening is not a universal feature of homeostatic plasticity in response to chronic activity deprivation.
Parent: NeuroscienceEntity: Homeostatic plasticitySub-entity: Action potential broadeningImpact: negativeDate: Apr 23, 2026Target: The reliability of action potential broadening as a homeostatic mechanism
Source posts
Unreliable homeostatic action potential broadening in cultured dissociated neurons
hypothes.is/a/xdj2lD8rEfGChPdoIhPHzA
**Reviewer #1 (Public review):**
\[Editors' note: The Reviewing Editor has assessed the revised manuscript without seeking further input from the original reviewers. The authors have addressed the main points raised during peer review, including…
0 boosts · 0 favs · 0 replies · Apr 23, 2026
Unreliable homeostatic action potential broadening in cultured dissociated neurons
hypothes.is/a/xgjzYj8rEfGktGOyzBPdBw
**eLife Assessment**
This study provides compelling evidence that action potential (AP) broadening is not a universal feature of homeostatic plasticity in response to chronic activity deprivation. By leveraging state-of-the-art methods across multiple…
0 boosts · 0 favs · 0 replies · Apr 23, 2026
Unreliable homeostatic action potential broadening in cultured dissociated neurons
hypothes.is/a/xabN9D8rEfGDUGeeFkYxxA
**Reviewer #2 (Public review):**
Summary:
This study reexamined the idea that action potential broadening serves as a homeostatic mechanism to compensate for changes in network activity. The key finding was that, while action potential broadening…
0 boosts · 0 favs · 0 replies · Apr 23, 2026
Unreliable homeostatic action potential broadening in cultured dissociated neurons
hypothes.is/a/xXbJ2D8rEfGB4I8kx3eSew
**Reviewer #3 (Public review):**
Summary:
The manuscript "Unreliable homeostatic action potential broadening in cultured dissociated neurons" by Ritzau-Jost et al. investigates action potential (AP) broadening as a mechanism underlying…
0 boosts · 0 favs · 0 replies · Apr 23, 2026
Unreliable homeostatic action potential broadening in cultured dissociated neurons
hypothes.is/a/xUd2TD8rEfGEyBPOj80mWA
**Author response:**
The following is the authors’ response to the original reviews.
> **Public Reviews:**
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> **Reviewer #1 (Public review):**
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> Summary:
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> Ritzau-Jost et al. investigate the potential contribution of AP broadening in homeostatic…
0 boosts · 0 favs · 0 replies · Apr 23, 2026
Unreliable homeostatic action potential broadening in cultured dissociated neurons
hypothes.is/a/xgjzYj8rEfGktGOyzBPdBw
**eLife Assessment**
This study provides compelling evidence that action potential (AP) broadening is not a universal feature of homeostatic plasticity in response to chronic activity deprivation. By leveraging state-of-the-art methods across multiple…
0 boosts · 0 favs · 0 replies · Apr 23, 2026
Unreliable homeostatic action potential broadening in cultured dissociated neurons
hypothes.is/a/xdj2lD8rEfGChPdoIhPHzA
**Reviewer #1 (Public review):**
\[Editors' note: The Reviewing Editor has assessed the revised manuscript without seeking further input from the original reviewers. The authors have addressed the main points raised during peer review, including…
0 boosts · 0 favs · 0 replies · Apr 23, 2026