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Intracellular zinc export during sperm capacitation regulates the function of the sperm-specific potassium channel Slo3.

TechnologyHealthcareApr 20, 2026score 0.173 posts · 0 replies across 1 instances
The thread discusses a scientific study on the role of intracellular zinc in regulating the sperm-specific potassium channel Slo3 during capacitation, highlighting its impact on sperm function and potential implications for fertility.

Claims

Intracellular zinc export during sperm capacitation regulates the function of the sperm-specific potassium channel Slo3.
Parent: BiotechnologyEntity: Sperm-specific potassium channel Slo3Impact: positiveDate: Apr 20, 2026Target: Intracellular zinc export during sperm capacitation regulates the function of the sperm-specific potassium channel Slo3.

Source posts

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Zinc is a Key Regulator of the Sperm-Specific K+ Channel (Slo3) Function hypothes.is/a/Bf_OLDzkEfGBVIcim0077A **Reviewer #1 (Public review):** Summary: In their manuscript, Andriani et al. show intracellular zinc is exported from sperm during capacitation and suppresses the alkalinization-induced hyperpolarization in sperm. Intracellular zinc inhibits…
0 boosts · 0 favs · 0 replies · Apr 20, 2026
@[email protected]
Zinc is a Key Regulator of the Sperm-Specific K+ Channel (Slo3) Function hypothes.is/a/Bi9pXDzkEfGmUc_1Oml4Ug **eLife Assessment** This study presents a valuable finding on the role of intracellular zinc as a regulator of the sperm-specific potassium channel Slo3, demonstrating that zinc export during capacitation contributes to alkalinization-induced…
0 boosts · 0 favs · 0 replies · Apr 20, 2026
@[email protected]
Zinc is a Key Regulator of the Sperm-Specific K+ Channel (Slo3) Function hypothes.is/a/BYWTljzkEfGfS2soVbeO9Q **Author response:** The following is the authors’ response to the original reviews. > **Public Reviews:** > > **Reviewer #1 (Public review):** > > Summary: > > In their manuscript, Andriani et al. show intracellular zinc is exported from sperm during…
0 boosts · 0 favs · 0 replies · Apr 20, 2026
@[email protected]
Zinc is a Key Regulator of the Sperm-Specific K+ Channel (Slo3) Function hypothes.is/a/Bf_OLDzkEfGBVIcim0077A **Reviewer #1 (Public review):** Summary: In their manuscript, Andriani et al. show intracellular zinc is exported from sperm during capacitation and suppresses the alkalinization-induced hyperpolarization in sperm. Intracellular zinc inhibits…
0 boosts · 0 favs · 0 replies · Apr 20, 2026