Modulating inter-mitochondrial contacts to increase membrane potential can mitigate blue light-induced mitochondrial dysfunction.

Modulating inter-mitochondrial contacts to increase membrane potential for mitigating blue light damage hypothes.is/a/1Za2MDyMEfGK7sPjnCIRTw **Reviewer #1 (Public review):** Summary: Blue light exposure has been shown to induce mitochondrial dysfunction, including reduced mitochondrial membrane potential (MMP). In the present study, the authors present a protein-based optogenetic…

Modulating inter-mitochondrial contacts to increase membrane potential for mitigating blue light damage hypothes.is/a/1cinijyMEfG6U-esi50HRQ **eLife Assessment** In this work, the authors demonstrated that blue light mediated mitochondrial contacts attenuated blue light induced mitochondrial dysfunction, and validated this in human cells and C. elegans. This valuable work has the potential…