mRNA imprinting involves the transcription apparatus influencing cytoplasmic post-transcriptional mechanisms through RNA-protein complexes.

mRNA Imprinting: transcription apparatus can remotely control cytoplasmic post-transcriptional mechanisms by dozens of proteins hypothes.is/a/3SbQSDyLEfG7d1uMgjGx1w **Reviewer #1 (Public review):** Summary: To understand the process of mRNA imprinting, the authors develop a series of unbiased methods to identify and follow proteins that associate with transcripts co-transcriptionally. The methods rely on RNA…

mRNA Imprinting: transcription apparatus can remotely control cytoplasmic post-transcriptional mechanisms by dozens of proteins hypothes.is/a/3LrK7DyLEfG-Q2eCJTVXqA **Reviewer #3 (Public review):** Summary: Various groups over the last several decades have provided many examples of proteins associating with nascent mRNA co-transcriptionally to influence gene expression at subsequent stages, including in the…

mRNA Imprinting: transcription apparatus can remotely control cytoplasmic post-transcriptional mechanisms by dozens of proteins hypothes.is/a/3VLFGDyLEfGXbcu9xFzESg **eLife Assessment** In this valuable study, the authors develop new approaches to investigate mRNA imprinting, a phenomenon in which RNA-protein complexes form in the nucleus to influence the fate of transcripts in the cytoplasm. They propose that…

mRNA Imprinting: transcription apparatus can remotely control cytoplasmic post-transcriptional mechanisms by dozens of proteins hypothes.is/a/3PLk6jyLEfG0cp9JhVF69A **Reviewer #2 (Public review):** Summary: The authors have provided valuable and solid evidence for the hypothesis, of which Choder is an early advocate, that transcription facilitates the assembly of an mRNA-protein complex that can affect the…