The endoderm of Styela clava has a dual developmental origin during metamorphosis.

Biology Evolutionary DevelopmentApr 20, 2026score 0.172 posts · 0 replies across 1 instances

The thread discusses a scientific study on the endoderm cell trajectory in the urochordate Styela clava, focusing on its developmental origin and evolution of the digestive tract. The study uses single-cell sequencing to explore endodermal lineage specification during metamorphosis, highlighting the dual origin of the digestive tract in these organisms.

Claims

Parent: BiologyEntity: Endoderm developmentSub-entity: Styela clavaImpact: positiveDate: Apr 20, 2026Target: The dual developmental origin of the endoderm in Styela clava

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The endoderm cell trajectory of urochordate Styela clava reveals the dual developmental origin and evolution of digestive tract

hypothes.is/a/rTBsADyLEfGSvV-QbX5bag

**eLife Assessment**  
  
This potentially important paper questions the evolutionary origin of the tunicate endoderm, using single-cell sequencing on a developmental series of the ascidian Styela clava that covers metamorphosis and gut development. The…

0 boosts · 0 favs · 0 replies · Apr 20, 2026

@[email protected]

The endoderm cell trajectory of urochordate Styela clava reveals the dual developmental origin and evolution of digestive tract

hypothes.is/a/rM2ewjyLEfGaeU_kCGwV7A

**Reviewer #2 (Public review):**  
  
This manuscript explores endodermal lineage specification during metamorphosis in Styela clava. As biphasic lifestyle organisms, the endoderm exists as a rudiment in the non-feeding larvae that differentiates…

0 boosts · 0 favs · 0 replies · Apr 20, 2026